This will be DNA vaccine in the future. However, I do NOT know the society acceptance to use lentivirus as a vector or NOT because many unknowns for lentivirus cDNA to integrate into host chromosome.  

   Virus-like particle (VLP) vaccine will be future trends. The strength of lentivirus vector is related to higher immunogenicity without the needs to use adjuvant. Dr. Collins group find that the mechanism of higher immunogenicity is related to stimulate higher innate immunity.The good part of innate immunity is to be induced at earlier time (even long before B -cell and T-cell immune responses) but also link to adaptive immunity.  In other words, the first encountering immune response to the pathogen is very important and that idea can be applied to improve vaccine. 

  Remind you to call your mother if you are out of Taipei while tomorrow is Mother's day.